PEAR1 anticorps (C-Term)

N° du produit ABIN6991445

Détail du produit anti-PEAR1 anticorps

Antigène: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEAR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: PEAR1 Antibody is affinity chromatography purified via peptide column.

Immunogène: PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1. The immunogen is located within the last 50 amino acids of PEAR1.

Isotype: IgG

Information d'application

Indications d'application: PEAR1 antibody can be used for detection of PEAR1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PEAR1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PEAR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PEAR1

Antigène: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Autre désignation: PEAR1 (PEAR1 Produits)

Synonymes: anticorps MEGF12, anticorps JEDI, anticorps 3110045G13Rik, anticorps Jedi-1, anticorps Megf12, anticorps RGD1305653, anticorps platelet endothelial aggregation receptor 1, anticorps PEAR1, anticorps pear1, anticorps Pear1

Sujet: PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated, the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

ID gène: 375033

NCBI Accession: NP_001073940

UniProt: Q5VY43