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N4BP1 anticorps (N-Term)

N4BP1 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991485
  • Antigène Voir toutes N4BP1 Anticorps
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 14
    • 1
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp N4BP1 est non-conjugé
    Application
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    At least three isoforms of N4BP1 are known to exist, this antibody will only detect the longest isoform.
    Purification
    N4BP1 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    N4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1. The immunogen is located within the first 50 amino acids of N4BP1.
    Isotype
    IgG
    Top Product
    Discover our top product N4BP1 Anticorps primaire
  • Indications d'application
    N4BP1 antibody can be used for detection of N4BP1 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    N4BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    N4BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
    Autre désignation
    N4BP1 (N4BP1 Produits)
    Synonymes
    anticorps AI481586, anticorps C81621, anticorps RGD1305179, anticorps wu:fi03b05, anticorps zgc:66437, anticorps NEDD4 binding protein 1, anticorps Nedd4 binding protein 1, anticorps nedd4 binding protein 1, anticorps nedd4 binding protein 1 L homeolog, anticorps N4BP1, anticorps N4bp1, anticorps n4bp1, anticorps n4bp1.L
    Sujet
    N4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
    ID gène
    9683
    NCBI Accession
    NP_694574
    UniProt
    O75113
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