ESRP1 anticorps (N-Term)

N° du produit ABIN6991490

Détail du produit anti-ESRP1 anticorps

Antigène: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Épitope: AA 30-80, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: RBM35A antibody is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist, this antibody will detect all five.

Purification: RBM35A Antibody is affinity chromatography purified via peptide column.

Immunogène: RBM35A antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RBM35A. The immunogen is located within amino acids 30 - 80 of RBM35A.

Isotype: IgG

Information d'application

Indications d'application: RBM35A antibody can be used for detection of RBM35A by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RBM35A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RBM35A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ESRP1

Antigène: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Autre désignation: RBM35A (ESRP1 Produits)

Synonymes: anticorps rbm35a, anticorps RBM35A, anticorps RMB35A, anticorps 2210008M09Rik, anticorps A630065D16, anticorps BC031468, anticorps Rbm35a, anticorps RGD1560481, anticorps wu:fi28a07, anticorps zgc:154050, anticorps epithelial splicing regulatory protein 1, anticorps epithelial splicing regulatory protein 1 L homeolog, anticorps ESRP1, anticorps esrp1.L, anticorps Esrp1, anticorps esrp1

Sujet: RBM35A Antibody: RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.

ID gène: 54845

NCBI Accession: NP_001030087

UniProt: Q6NXG1