ZNF219 anticorps (N-Term)

N° du produit ABIN6991505

Détail du produit anti-ZNF219 anticorps

Antigène: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Épitope: AA 90-140, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF219 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.

Purification: ZFP219 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219. The immunogen is located within amino acids 90 - 140 of ZFP219.

Isotype: IgG

Information d'application

Indications d'application: ZFP219 antibody can be used for detection of ZFP219 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZFP219 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZFP219 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZNF219

Antigène: ZNF219 (Zinc Finger Protein 219 (ZNF219))

Autre désignation: ZFP219 (ZNF219 Produits)

Synonymes: anticorps ZNF219, anticorps ZFP219, anticorps Znf219, anticorps 2010302A17Rik, anticorps zinc finger protein 219, anticorps ZNF219, anticorps Zfp219

Sujet: ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.

Poids moléculaire: Predicted: 80 kDa

Observed: 78 kDa

ID gène: 51222

NCBI Accession: NP_001095142

UniProt: Q9P2Y4