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PRR5L anticorps (AA 220-270)

PRR5L Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991524
  • Antigène Voir toutes PRR5L Anticorps
    PRR5L (Proline Rich 5 Like (PRR5L))
    Épitope
    • 1
    • 1
    AA 220-270
    Reactivité
    Humain, Souris
    Hôte
    • 3
    Lapin
    Clonalité
    • 3
    Polyclonal
    Conjugué
    • 3
    Cet anticorp PRR5L est non-conjugé
    Application
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    Purification
    PRR5L Antibody is affinity chromatography purified via peptide column.
    Immunogène
    PRR5L antibody was raised against a 17 amino acid synthetic peptide near the center of human PRR5L. The immunogen is located within amino acids 220 - 270 of PRR5L.
    Isotype
    IgG
  • Indications d'application
    PRR5L antibody can be used for detection of PRR5L by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PRR5L Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    PRR5L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    PRR5L (Proline Rich 5 Like (PRR5L))
    Autre désignation
    PRR5L (PRR5L Produits)
    Synonymes
    anticorps PROTOR2, anticorps 2600010E01Rik, anticorps 4833411O04Rik, anticorps Protor-2, anticorps Protor2, anticorps RGD1309969, anticorps PRR5L, anticorps FLJ14213, anticorps proline rich 5 like, anticorps PRR5L, anticorps Prr5l, anticorps prr5l
    Sujet
    PRR5L Antibody: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
    ID gène
    79899
    NCBI Accession
    NP_001153639
    UniProt
    Q6MZQ0
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