At least two isoforms of TMEM204 are known to exist, this antibody will recognize both isoforms.
Purification
TMEM204 Antibody is affinity chromatography purified via peptide column.
Immunogène
TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204. The immunogen is located within the last 50 amino acids of TMEM204.
TMEM204
Reactivité: Humain, Souris, Rat
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
TMEM204 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
TMEM204 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.