At least two isoforms of UHRF1BP1L are known to exist, this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1
Purification
UHRF1BP1L Antibody is affinity chromatography purified via peptide column.
Immunogène
UHRF1BP1L antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1L. The immunogen is located within amino acids 980 - 1030 of UHRF1BP1L.
UHRF1BP1L
Reactivité: Humain, Souris, Rat
ELISA, WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
UHRF1BP1L antibody can be used for detection of UHRF1BP1L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
UHRF1BP1L Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
UHRF1BP1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
UHRF1BP1L
(UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))
UHRF1BP1L Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.