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PRICKLE2 anticorps (AA 420-470)

PRICKLE2 Reactivité: Humain, Souris, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991607
  • Antigène Voir toutes PRICKLE2 Anticorps
    PRICKLE2 (Prickle Homolog 2 (PRICKLE2))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 420-470
    Reactivité
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 7
    Lapin
    Clonalité
    • 7
    Polyclonal
    Conjugué
    • 7
    Cet anticorp PRICKLE2 est non-conjugé
    Application
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Specificité
    Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.
    Purification
    PRICKLE2 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    PRICKLE2 antibody was raised against a 15 amino acid synthetic peptide near the center of human PRICKLE2. The immunogen is located within amino acids 420 - 470 of PRICKLE2.
    Isotype
    IgG
    Top Product
    Discover our top product PRICKLE2 Anticorps primaire
  • Indications d'application
    PRICKLE2 antibody can be used for detection of PRICKLE2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PRICKLE2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    PRICKLE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    PRICKLE2 (Prickle Homolog 2 (PRICKLE2))
    Autre désignation
    PRICKLE2 (PRICKLE2 Produits)
    Synonymes
    anticorps EPM5, anticorps 6230400G14Rik, anticorps 6720451F06Rik, anticorps mpk2, anticorps cb886, anticorps im:7138215, anticorps pk2, anticorps prickle planar cell polarity protein 2, anticorps prickle homolog 2b, anticorps PRICKLE2, anticorps Prickle2, anticorps prickle2b
    Sujet
    PRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
    ID gène
    166336
    NCBI Accession
    NP_942559
    UniProt
    Q7Z3G6
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