DELE1/KIAA0141 anticorps (N-Term)

N° du produit ABIN6991710

Détail du produit anti-DELE1/KIAA0141 anticorps

Antigène: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Épitope: N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DELE1/KIAA0141 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: DELE Antibody is affinity chromatography purified via peptide column.

Immunogène: DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.

Isotype: IgG

Information d'application

Indications d'application: DELE antibody can be used for detection of DELE by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DELE Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DELE1/KIAA0141

Antigène: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Autre désignation: DELE (DELE1 Produits)

Synonymes: anticorps KIAA0141, anticorps MGC139304, anticorps DELE, anticorps 2700004E22Rik, anticorps Dele, anticorps Kiaa0141, anticorps KIAA0141, anticorps KIAA0141 ortholog, anticorps RIKEN cDNA 0610009O20 gene, anticorps SEL1 domain containing protein RGD735029, anticorps KIAA0141, anticorps 0610009O20Rik, anticorps RGD735029

Sujet: DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α, and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

ID gène: 9812

NCBI Accession: NP_055588

UniProt: Q14154