MECR anticorps (C-Term)

N° du produit ABIN6991794

Détail du produit anti-MECR anticorps

Antigène: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Épitope: AA 300-350, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECR est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.

Purification: MECR Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR. The immunogen is located within amino acids 300 - 350 of MECR.

Isotype: IgG

Information d'application

Indications d'application: MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MECR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MECR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur MECR

Antigène: MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

Autre désignation: MECR (MECR Produits)

Synonymes: anticorps CGI-63, anticorps FASN2B, anticorps NRBF1, anticorps AI195831, anticorps Nrbf1, anticorps mitochondrial trans-2-enoyl-CoA reductase, anticorps MECR, anticorps Mecr

Sujet: MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

Poids moléculaire: Predicted: 41 kDa

ID gène: 51102

NCBI Accession: NP_057095

UniProt: Q9BV79