RRAS2 anticorps (C-Term)

N° du produit ABIN6991827

Détail du produit anti-RRAS2 anticorps

Antigène: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Two isoforms of RRAS2 exists as a result of alternative splicing event.

Purification: RRAS2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal RRAS2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human RRAS2. The immunogen is located within the last 50 amino acids of RRAS2.

Isotype: IgG

Information d'application

Indications d'application: RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RRAS2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RRAS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur RRAS2

Antigène: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Autre désignation: RRAS2 (RRAS2 Produits)

Synonymes: anticorps TC21, anticorps 2610016H24Rik, anticorps C86394, anticorps Ras-related protein R-Ras2, anticorps RAS related 2, anticorps related RAS viral (r-ras) oncogene 2, anticorps related RAS viral (r-ras) oncogene homolog 2, anticorps TVAG_453070, anticorps Bm1_46660, anticorps RRAS2, anticorps Rras2

Sujet: RRAS2 Antibody: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60 % . RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.

Poids moléculaire: 22 kDa

ID gène: 22800

NCBI Accession: NP_036382

UniProt: P62070