SHISA4 anticorps (AA 100-150)

N° du produit ABIN6991838

Détail du produit anti-SHISA4 anticorps

Antigène: SHISA4 (Shisa Homolog 4 (SHISA4))

Épitope: AA 100-150

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHISA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: SHISA4 antibody is predicted to not cross-react with other SHISA protein family members.

Purification: SHISA4 Antibody is affinity chromatography purified via peptide column.

Immunogène: SHISA4 antibody was raised against a 15 amino acid peptide near the center of human SHISA4 . The immunogen is located within amino acids 100 - 150 of SHISA4.

Isotype: IgG

Information d'application

Indications d'application: SHISA4 Antibody can be used for detection of SHISA4 by Western blot starting at 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SHISA4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SHISA4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SHISA4

Antigène: SHISA4 (Shisa Homolog 4 (SHISA4))

Autre désignation: SHISA4 (SHISA4 Produits)

Synonymes: anticorps C1orf40, anticorps TMEM58, anticorps 9330132O05Rik, anticorps Tmem58, anticorps mShisa4, anticorps shisa family member 4, anticorps SHISA4, anticorps Shisa4

Sujet: SHISA4 Antibody: SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.

Poids moléculaire: Predicted: 22 kDa

Observed: 24 kDa

ID gène: 149345

NCBI Accession: NP_937792

UniProt: Q96DD7