CISD2 anticorps (AA 40-90)
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- Antigène Voir toutes CISD2 Anticorps
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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Épitope
- AA 40-90
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CISD2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- CISD2 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2. The immunogen is located within amino acids 40 - 90 of CISD2.
- Isotype
- IgG
- Top Product
- Discover our top product CISD2 Anticorps primaire
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- Indications d'application
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CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- CISD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- CISD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
- Autre désignation
- CISD2 (CISD2 Produits)
- Synonymes
- anticorps ERIS, anticorps Miner1, anticorps NAF-1, anticorps WFS2, anticorps ZCD2, anticorps 1500009M05Rik, anticorps 1500026J14Rik, anticorps 1500031D15Rik, anticorps AI848398, anticorps B630006A20Rik, anticorps Noxp70, anticorps Zcd2, anticorps RGD1566242, anticorps zgc:64148, anticorps eris, anticorps miner1, anticorps wfs2, anticorps zcd2, anticorps cisd2, anticorps BcDNA:RE49709, anticorps Dmel\\CG1458, anticorps CDGSH iron sulfur domain 2, anticorps CDGSH iron sulfur domain 2 L homeolog, anticorps CDGSH iron sulfur domain 2 S homeolog, anticorps CISD2, anticorps Cisd2, anticorps cisd2, anticorps cisd2.L, anticorps cisd2.S
- Sujet
- CISD2 Antibody: Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
- Poids moléculaire
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Predicted: 15 kDa
Observed: 15 kDa - ID gène
- 493856
- NCBI Accession
- NP_001008389
- UniProt
- Q8N5K1
- Pathways
- Activation of Innate immune Response
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