ANKRD15 anticorps (N-Term)

N° du produit ABIN6991851

Détail du produit anti-ANKRD15 anticorps

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.

Purification: KANK1 Antibody is affinity chromatography purified via peptide column.

Immunogène: KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 . The immunogen is located within the first 50 amino acids of KANK1.

Isotype: IgG

Information d'application

Indications d'application: KANK1 Antibody can be used for detection of KANK1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KANK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KANK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1 (ANKRD15 Produits)

Synonymes: anticorps ANKRD15, anticorps CPSQ2, anticorps KANK, anticorps A930031B09Rik, anticorps AU015049, anticorps AW121052, anticorps Ankrd15, anticorps D330024H06Rik, anticorps mKIAA0172, anticorps KANK1, anticorps ankrd15, anticorps kank1.2, anticorps DMRT1, anticorps KN motif and ankyrin repeat domains 1, anticorps KN motif and ankyrin repeat domains 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1, anticorps KANK1, anticorps Kank1, anticorps kank1.L, anticorps DMRT1

Sujet: KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.

Poids moléculaire: Predicted: 149 kDa

Observed: 150 kDa

ID gène: 23189

NCBI Accession: NP_055973

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization