Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
Two alternatively spliced transcript variants encoding different isoforms have been identified.
Purification
KANK3 Antibody is affinity chromatography purified via peptide column.
Immunogène
KANK3 antibody was raised against an 18 amino acid peptide near the amino terminus of human KANK3 . The immunogen is located within amino acids 50 - 100 of KANK3.
KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.