KHDC1 anticorps (N-Term)

N° du produit ABIN6991883

Détail du produit anti-KHDC1 anticorps

Antigène: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Épitope: AA 30-80, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDC1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: KHDC1 antibody is human, mouse and rat reactive. At least three isoforms of KHDC1 are known to exist, this antibody will only detect the longest isoform.

Purification: KHDC1 Antibody is affinity chromatography purified via peptide column.

Immunogène: KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1. The immunogen is located within amino acids 30 - 80 of KHDC1.

Isotype: IgG

Information d'application

Indications d'application: KHDC1 antibody can be used for detection of KHDC1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KHDC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KHDC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KHDC1

Antigène: KHDC1 (KH Homology Domain Containing 1 (KHDC1))

Autre désignation: KHDC1 (KHDC1 Produits)

Synonymes: anticorps C6orf148, anticorps NDG1, anticorps bA257K9.4, anticorps Khdc1c, anticorps KH domain containing 1, anticorps KH homology domain containing 1, anticorps KHDC1, anticorps Khdc1

Sujet: KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).

Poids moléculaire: Predicted: 18 kDa

Observed: 26 kDa

ID gène: 80759

NCBI Accession: NP_085045

UniProt: Q4VXA5