Western Blotting (WB), ELISA, Immunofluorescence (IF)
Specificité
IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.
Purification
IL-28B Antibody is affinity chromatography purified via peptide column.
Immunogène
IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B. The immunogen is located within amino acids 120 - 170 of IL-28B .
Interleukin 28 (IL-28B), also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1). The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2,3). All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1).