TMEM107 anticorps (N-Term)

N° du produit ABIN6991906

Détail du produit anti-TMEM107 anticorps

Antigène: TMEM107 (Transmembrane Protein 107 (TMEM107))

Épitope: AA 20-70, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM107 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.

Purification: TMEM107 Antibody is affinity chromatography purified via peptide column.

Immunogène: TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. The immunogen is located within amino acids 20 - 70 of TMEM107 .

Isotype: IgG

Information d'application

Indications d'application: TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM107 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TMEM107

Antigène: TMEM107 (Transmembrane Protein 107 (TMEM107))

Autre désignation: TMEM107 (TMEM107 Produits)

Synonymes: anticorps zgc:77926, anticorps MGC157051, anticorps GRVS638, anticorps PRO1268, anticorps 1110004B13Rik, anticorps 2810049P21Rik, anticorps transmembrane protein 107, anticorps Transmembrane protein 107, anticorps transmembrane protein 107 L homeolog, anticorps tmem107, anticorps TMEM107, anticorps Tmem107, anticorps Tsp_08866, anticorps tm107, anticorps tmem107.L

Sujet: Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).

Poids moléculaire: Predicted: 16 kDa

Observed: 19kDa

ID gène: 84314

NCBI Accession: NP_115730

UniProt: Q6UX40