ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
IL-1F10 antibody is human, mouse and rat reactive. Two isoforms of IL-1F10 exist.
Purification
IL-1F10 antibody is affinity chromatography purified via peptide column.
Immunogène
Anti-IL-1F10 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human IL-1F10. The immunogen is located within the last 50 amino acids of IL-1F10.
anticorps FIL1-theta, anticorps IL-1HY2, anticorps IL-38, anticorps IL1-theta, anticorps IL1HY2, anticorps interleukin 1 family, member 10, anticorps interleukin 1 family member 10, anticorps Il1f10, anticorps IL1F10
Sujet
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).