FIL1h anticorps (C-Term)

N° du produit ABIN6991916

Détail du produit anti-FIL1h anticorps

Antigène: FIL1h (Interleukin 1 eta (FIL1h))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIL1h est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: IL-36B antibody is human specific. At least two isoforms of IL-36B are known to exist, this antibody will only detect the longer isoform. IL-36B antibody will not cross-react with IL-36A or IL-36G.

Purification: IL-36B antibody is affinity chromatography purified via peptide column.

Immunogène: IL-36B antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-36B. The immunogen is located within the last 50 amino acids of IL-36B.

Isotype: IgG

Information d'application

Indications d'application: IL-36B antibody can be used for detection of IL-36B by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-36B antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-36B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur FIL1h

Antigène: FIL1h (Interleukin 1 eta (FIL1h))

Autre désignation: IL-36B (FIL1h Produits)

Synonymes: anticorps 2310043N20Rik, anticorps Il36b, anticorps FIL1, anticorps FIL1-(ETA), anticorps FIL1H, anticorps FILI-(ETA), anticorps IL-1F8, anticorps IL-1H2, anticorps IL1-ETA, anticorps IL1F8, anticorps IL1H2, anticorps Il1f8, anticorps interleukin 1 family, member 8, anticorps interleukin 36 beta, anticorps interleukin 36, beta, anticorps Il1f8, anticorps IL36B, anticorps Il36b

Sujet: IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).

Poids moléculaire: Predicted: 18 kDa

Observed: 17 kDa

ID gène: 27177

NCBI Accession: NP_055253

UniProt: Q9NZH7