BHLHA15 antibody is human, mouse and rat reactive.
Purification
BHLHA15 antibody is affinity chromatography purified via peptide column.
Immunogène
BHLHA15 antibody was raised against a 18 amino acid peptide near the center of human BHLHA15. The immunogen is located within amino acids 60 - 110 of BHLHA15.
BHLHA15
Reactivité: Humain, Souris
WB, FACS
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
BHLHA15 antibody can be used for detection of BHLHA15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
BHLHA15 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
BHLHA15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
BHLHA15
(Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))
anticorps BHLHB8, anticorps MIST1, anticorps 1810009C13Rik, anticorps Bhlhb8, anticorps MIST-1, anticorps Mist1, anticorps bHlH, anticorps basic helix-loop-helix family member a15, anticorps basic helix-loop-helix family, member a15, anticorps BHLHA15, anticorps Bhlha15
Sujet
BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain (3). It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development (4).