UBIAD1 antibody is affinity chromatography purified via peptide column.
Immunogène
UBIAD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human UBIAD1. The immunogen is located within amino acids 210 - 260 of UBIAD1.
UBIAD1
Reactivité: Humain
Hôte: Lapin
Polyclonal
Alexa Fluor 750
Indications d'application
UBIAD1 antibody can be used for detection of UBIAD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
UBIAD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
UBIAD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1). Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2). Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3).