IFIT1 anticorps (C-Term)

N° du produit ABIN6991993

Détail du produit anti-IFIT1 anticorps

Antigène: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Épitope: AA 290-340, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family.

Purification: IFIT1 antibody is affinity chromatography purified via peptide column.

Immunogène: IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1. The immunogen is located within amino acids 290 - 340 of IFIT1.

Isotype: IgG

Information d'application

Indications d'application: IFIT1 antibody can be used for detection of IFIT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IFIT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IFIT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur IFIT1

Antigène: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Autre désignation: IFIT1 (IFIT1 Produits)

Synonymes: anticorps C56, anticorps G10P1, anticorps IFI-56, anticorps IFI-56K, anticorps IFI56, anticorps IFIT-1, anticorps IFNAI1, anticorps ISG56, anticorps P56, anticorps RNM561, anticorps Ifi56, anticorps Garg16, anticorps DKFZp469C2331, anticorps interferon induced protein with tetratricopeptide repeats 1, anticorps interferon-induced protein with tetratricopeptide repeats 1, anticorps IFIT1, anticorps Ifit1, anticorps LOC488947, anticorps ifit1, anticorps LOC100058990, anticorps LOC100139670, anticorps LOC100475782

Sujet: The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).

Poids moléculaire: Predicted: 53 kDa

Observed: 53 kDa

ID gène: 3434

NCBI Accession: NP_001539

UniProt: P09914

Pathways: Hepatitis C