USP25 anticorps (AA 470-520)

N° du produit ABIN6991995

Détail du produit anti-USP25 anticorps

Antigène: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Épitope: AA 470-520

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP25 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: USP25 antibody is human and mouse reactive. Multiple isoforms of USP25 are known to exist.

Purification: USP25 antibody is affinity chromatography purified via peptide column.

Immunogène: USP25 antibody was raised against a 17 amino acid peptide near the center of human USP25. The immunogen is located within amino acids 470 - 520 of USP25.

Isotype: IgG

Information d'application

Indications d'application: USP25 antibody can be used for detection of USP25 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: USP25 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: USP25 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur USP25

Antigène: USP25 (Ubiquitin Specific Peptidase 25 (USP25))

Autre désignation: USP25 (USP25 Produits)

Synonymes: anticorps USP25, anticorps zgc:55791, anticorps wu:fi33c05, anticorps wu:fo67e06, anticorps wu:fp97a04, anticorps usp25, anticorps MGC81666, anticorps usp21, anticorps USP21, anticorps ubiquitin specific peptidase 25, anticorps universal stress protein UspA, anticorps ubiquitin specific peptidase 25 L homeolog, anticorps USP25, anticorps RR_RS03930, anticorps usp25, anticorps usp25.L, anticorps Usp25

Sujet: USP25 (ubiquitin specific peptidase 25), also known as USP21, belongs to the peptidase C19 family and is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response (1). It contains one UBA-like domain and two UIM (ubiquitin-interacting motif) repeats. Due to alternative splicing events, USP25 is expressed as two short, ubiquitously expressed isoforms and one long, muscle-specific isoform (2). The long isoform of USP25 (USP25m) is upregulated in myogenesis and is implicated in regulation of muscular differentiation and function. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17-triggered signaling (3,4).

Poids moléculaire: Predicted: 116 kDa

Observed: 105 kDa

ID gène: 29761

NCBI Accession: NP_037528

UniProt: Q9UHP3