WAPAL anticorps (N-Term)

N° du produit ABIN6992007

Détail du produit anti-WAPAL anticorps

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Épitope: AA 30-80, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WAPAL est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.

Purification: WAPL antibody is affinity chromatography purified via peptide column.

Immunogène: WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL. The immunogen is located within amino acids 30 - 80 of WAPL.

Isotype: IgG

Information d'application

Indications d'application: WAPL antibody can be used for detection of WAPL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: WAPL antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: WAPL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur WAPAL

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Autre désignation: WAPL (WAPAL Produits)

Synonymes: anticorps RGD1308960, anticorps FOE, anticorps KIAA0261, anticorps WAPL, anticorps 2410073G16, anticorps A530089A20Rik, anticorps BC037674, anticorps mKIAA0261, anticorps mWAPL, anticorps WAPL cohesin release factor, anticorps Wapl, anticorps WAPL, anticorps wapl

Sujet: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1). It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1) (1,2,4). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits (3,4). WAPL is a new regulator of the development and metastasis of cancerous tissue (4,5).

Poids moléculaire: Predicted: 131 kDa

Observed: 140 kDa

ID gène: 23063

NCBI Accession: NP_055860

UniProt: Q7Z5K2

Pathways: Chromatin Binding