DOCK8 anticorps (C-Term)

N° du produit ABIN6992016

Détail du produit anti-DOCK8 anticorps

Antigène: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.

Purification: DOCK8 antibody is affinity chromatography purified via peptide column.

Immunogène: DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8. The immunogen is located within the last 50 amino acids of DOCK8.

Isotype: IgG

Information d'application

Indications d'application: DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DOCK8 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DOCK8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur DOCK8

Antigène: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Autre désignation: DOCK8 (DOCK8 Produits)

Synonymes: anticorps im:7154406, anticorps si:dkey-91m11.1, anticorps MRD2, anticorps ZIR8, anticorps 1200017A24Rik, anticorps 5830472H07Rik, anticorps A130095G14Rik, anticorps AI461977, anticorps dedicator of cytokinesis 8, anticorps dock8, anticorps DOCK8, anticorps Dock8

Sujet: The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).

Poids moléculaire: Predicted: 166, 220, 231 kDa

Observed: 220, 230 kDa

ID gène: 81704

NCBI Accession: NP_982272

UniProt: Q8NF50