NOX3 anticorps (N-Term)
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- Antigène Voir toutes NOX3 Anticorps
- NOX3 (NADPH Oxidase 3 (NOX3))
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Épitope
- AA 110-160, N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOX3 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.
- Purification
- NOX3 antibody is affinity chromatography purified via peptide column.
- Immunogène
- NOX3 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX3. The immunogen is located within amino acids 110 - 160 of NOX3.
- Isotype
- IgG
- Top Product
- Discover our top product NOX3 Anticorps primaire
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- Indications d'application
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NOX3 antibody can be used for detection of NOX3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- NOX3 antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- NOX3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- NOX3 (NADPH Oxidase 3 (NOX3))
- Autre désignation
- NOX3 (NOX3 Produits)
- Synonymes
- anticorps GP91-3, anticorps het, anticorps nmf250, anticorps MOX-2, anticorps NADPH oxidase 3, anticorps Nox3, anticorps NOX3, anticorps nox3
- Sujet
- The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4).
- Poids moléculaire
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Predicted: 62 kDa
Observed: 72 kDa - ID gène
- 50508
- NCBI Accession
- NP_056533
- UniProt
- Q9HBY0
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