PRRX1 anticorps (AA 70-120)

N° du produit ABIN6992105

Détail du produit anti-PRRX1 anticorps

Antigène: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Épitope: AA 70-120

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRRX1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist, this antibody will detect both isoforms.

Purification: PRRX1 antibody is affinity chromatography purified via peptide column.

Immunogène: PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1. The immunogen is located within amino acids 70 - 120 of PRRX1.

Isotype: IgG

Information d'application

Indications d'application: PRRX1 antibody can be used for detection of PRRX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRRX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PRRX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PRRX1

Antigène: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Autre désignation: PRRX1 (PRRX1 Produits)

Sujet: The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5).

Poids moléculaire: Predicted: 27 kDa

Observed: 26 kDa

ID gène: 5396

NCBI Accession: NP_073207

UniProt: P54821