Western Blotting (WB), ELISA, Immunofluorescence (IF)
Specificité
MKRN3 antibody is human specific. MKRN3 antibody is predicted to not cross-react with other members of the MKRN protein family.
Purification
MKRN3 antibody is affinity chromatography purified via peptide column.
Immunogène
MKRN3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MKRN3. The immunogen is located within amino acids 400 - 450 of MKRN3.
anticorps CPPB2, anticorps D15S9, anticorps RNF63, anticorps ZFP127, anticorps ZNF127, anticorps D7H15S9-1, anticorps Zfp127, anticorps makorin ring finger protein 3, anticorps makorin, ring finger protein, 3, anticorps MKRN3, anticorps Mkrn3
Sujet
The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome (1), but a deletion of the gene does not (2). A deficiency of MKRN3 has been shown to cause central precocious puberty in humans (3).