C2CD3 anticorps (AA 1490-1540)

N° du produit ABIN6992132

Détail du produit anti-C2CD3 anticorps

Antigène: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Épitope: AA 1490-1540

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C2CD3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: C2CD3 antibody is human, mouse and rat reactive.

Purification: C2CD3 antibody is affinity chromatography purified via peptide column.

Immunogène: C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. The immunogen is located within amino acids 1490 - 1540 of C2CD3.

Isotype: IgG

Information d'application

Indications d'application: C2CD3 antibody can be used for detection of C2CD3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: C2CD3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: C2CD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur C2CD3

Antigène: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Autre désignation: C2CD3 (C2CD3 Produits)

Synonymes: anticorps AU020772, anticorps RGD1307366, anticorps C2 calcium dependent domain containing 3, anticorps C2 calcium-dependent domain containing 3, anticorps C2CD3, anticorps C2cd3

Sujet: C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5).

Poids moléculaire: Predicted: 216, 259 kDa

Observed: 255 kDa

ID gène: 26005

NCBI Accession: NP_001273506

UniProt: Q4AC94