PACS1 anticorps (AA 430-480)
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- Antigène Voir toutes PACS1 Anticorps
- PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
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Épitope
- AA 430-480
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PACS1 est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
- Purification
- PACS1 antibody is affinity chromatography purified via peptide column.
- Immunogène
- PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.
- Isotype
- IgG
- Top Product
- Discover our top product PACS1 Anticorps primaire
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- Indications d'application
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PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
- Autre désignation
- PACS1 (PACS1 Produits)
- Synonymes
- anticorps MRD17, anticorps AI325977, anticorps Pacs-1, anticorps phosphofurin acidic cluster sorting protein 1, anticorps PACS1, anticorps Pacs1
- Sujet
- The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).
- Poids moléculaire
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Predicted: 106 kDa
Observed: 105 kDa - ID gène
- 55690
- NCBI Accession
- NP_060496
- UniProt
- Q6VY07
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