KIR2DS2 anticorps (C-Term)

N° du produit ABIN6992145

Détail du produit anti-KIR2DS2 anticorps

Antigène: KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIR2DS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.

Purification: KIR2DS2 antibody is affinity chromatography purified via peptide column.

Immunogène: KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.

Isotype: IgG

Information d'application

Indications d'application: KIR2DS2 antibody can be used for detection of KIR2DS2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KIR2DS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KIR2DS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KIR2DS2

Antigène: KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))

Autre désignation: KIR2DS2 (KIR2DS2 Produits)

Synonymes: anticorps 183ActI, anticorps CD158J, anticorps CD158b, anticorps NKAT5, anticorps cl-49, anticorps killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2, anticorps KIR2DS2

Sujet: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).

Poids moléculaire: Predicted: 28, 33, 37 kDa

Observed: 34, 42 kDa

ID gène: 100132285

NCBI Accession: NP_036444

UniProt: P43631