SUSD3 anticorps (AA 120-170)

N° du produit ABIN6992182

Détail du produit anti-SUSD3 anticorps

Antigène: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Épitope: AA 120-170

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUSD3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Specificité: SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.

Purification: SUSD3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3. The immunogen is located within amino acids 120 - 170 of SUSD3.

Isotype: IgG

Information d'application

Indications d'application: SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SUSD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SUSD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SUSD3

Antigène: SUSD3 (Sushi Domain Containing 3 (SUSD3))

Autre désignation: SUSD3 (SUSD3 Produits)

Synonymes: anticorps 1700017I11Rik, anticorps 2810440J20Rik, anticorps sushi domain containing 3, anticorps SUSD3, anticorps Susd3

Sujet: Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).

Poids moléculaire: Predicted: 16, 22, 23, 28 kDa

Observed: 23 kDa

ID gène: 203328

NCBI Accession: NP_659443

UniProt: Q96L08