MLXIP anticorps (N-Term)

N° du produit ABIN6992189

Détail du produit anti-MLXIP anticorps

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLXIP est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: MLXIP Antibody is affinity chromatography purified via peptide column.

Immunogène: MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.

Isotype: IgG

Information d'application

Indications d'application: MLXIP antibody can be used for Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MLXIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MLXIP

Antigène: MLXIP (MLX Interacting Protein (MLXIP))

Autre désignation: MLXIP (MLXIP Produits)

Synonymes: anticorps MGC83884, anticorps si:ch211-110p13.4, anticorps MIR, anticorps MONDOA, anticorps bHLHe36, anticorps AW228700, anticorps B930074I24, anticorps Mir, anticorps mKIAA0867, anticorps RGD1560774, anticorps MLX interacting protein, anticorps MLX interacting protein L homeolog, anticorps MLXIP, anticorps mlxip.L, anticorps mlxip, anticorps Mlxip

Sujet: MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).

Poids moléculaire: Predicted: 20 kDa

Observed: 21 kDa

ID gène: 22877

NCBI Accession: NP_055753

UniProt: Q9HAP2