SIGLEC15 anticorps (AA 270-320)

N° du produit ABIN6992284

Détail du produit anti-SIGLEC15 anticorps

Antigène: SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

Épitope: AA 270-320

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC15 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: SIGLEC15 Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-SIGLEC15 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human SIGLEC15. The immunogen is located within amino acids 270-320 of SIGLEC15.

Isotype: IgG

Information d'application

Indications d'application: WB: 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIGLEC15 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIGLEC15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIGLEC15

Antigène: SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

Autre désignation: SIGLEC15 (SIGLEC15 Produits)

Synonymes: anticorps RGD1565948, anticorps CD33L3, anticorps HsT1361, anticorps SIGLEC-15, anticorps Cd33l3, anticorps EG620235, anticorps SIGLEC-I, anticorps sialic acid binding Ig-like lectin 15, anticorps sialic acid binding Ig like lectin 15, anticorps Siglec15, anticorps SIGLEC15

Sujet: SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.

Poids moléculaire: Predicted: 36kD

Observed: 34-36kD kDa

ID gène: 284266

NCBI Accession: NP_998767

UniProt: Q6ZMC9