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SARS-CoV-2 ORF7a anticorps (C-Term)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6992305
  • Antigène Tous les produits SARS-CoV-2 ORF7a
    SARS-CoV-2 ORF7a
    Épitope
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 4
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Hôte
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 4
    • 1
    Polyclonal
    Conjugué
    • 5
    Cet anticorp SARS-CoV-2 ORF7a est non-conjugé
    Application
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA
    Purification
    SARS-CoV-2 (COVID-19) ORF7a Antibody is affinity chromatography purified via peptide column.
    Immunogène
    Anti-SARS-CoV-2 (COVID-19) ORF7a antibody was raised against a peptide corresponding to 9 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) ORF7a protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF7a protein.
    Isotype
    IgG
  • Indications d'application
    Antibody validated: SARS-CoV-2 (COVID-19) ORF7a antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) ORF7a antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    SARS-CoV-2 (COVID-19) ORF7a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    SARS-CoV-2 ORF7a
    Abstract
    SARS-CoV-2 ORF7a Produits
    Synonymes
    anticorps ORF7a protein, anticorps ORF7a
    Classe de substances
    Viral Protein
    Sujet
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF7a and ORF7a. ORF7a plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. It acts by binding to BST2 thereby interfering with its glycosylation. It may suppress small interfering RNA (siRNA) and may bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes (3).
    Poids moléculaire
    14kD kDa
    ID gène
    43740573
    UniProt
    P0DTC7
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