PLAUR anticorps

N° du produit ABIN7234357

Détail du produit anti-PLAUR anticorps

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogène: Recombinant Human Urokinase plasminogen activator surface receptor protein

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.85 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: PLAUR (PLAUR Produits)

Synonymes: anticorps Cd87, anticorps u-PAR, anticorps uPAR, anticorps CD87, anticorps U-PAR, anticorps UPAR, anticorps URKR, anticorps Par, anticorps Plaur3, anticorps uPAR-2, anticorps uPAR-3, anticorps PLAUR, anticorps plasminogen activator, urokinase receptor, anticorps Plaur, anticorps PLAUR

Sujet: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

ID gène: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process