Synaptotagmin 3 anticorps

N° du produit ABIN7235576

Détail du produit anti-Synaptotagmin 3 anticorps

Antigène: Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptotagmin 3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human SYT3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Synaptotagmin 3

Antigène: Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))

Autre désignation: SYT3 (SYT3 Produits)

Synonymes: anticorps SytIII, anticorps AI385753, anticorps sytIII, anticorps SIII, anticorps synaptotagmin 3, anticorps synaptotagmin III, anticorps SYT3, anticorps Syt3

Sujet: Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.

UniProt: Q9BQG1

Pathways: Synaptic Vesicle Exocytosis