anticorps AA589454, anticorps wu:fc37d06, anticorps zgc:73323, anticorps zgc:77755, anticorps AUP1, lipid droplet regulating VLDL assembly factor, anticorps ancient ubiquitous protein 1, anticorps ancient ubiquitous protein 1 S homeolog, anticorps AUP1, anticorps aup1, anticorps Aup1, anticorps aup1.S
Sujet
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.