ELP2 anticorps

N° du produit ABIN7236188

Détail du produit anti-ELP2 anticorps

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELP2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ELP2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ELP2

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Autre désignation: ELP2 (ELP2 Produits)

Sujet: One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus