ELP2 anticorps

N° du produit ABIN7236188

Détail du produit anti-ELP2 anticorps

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELP2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human ELP2

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ELP2

Antigène: ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))

Autre désignation: ELP2 (ELP2 Produits)

Synonymes: anticorps zgc:153559, anticorps SHINC-2, anticorps STATIP1, anticorps StIP, anticorps AU023723, anticorps Epl2, anticorps StIP1, anticorps Statip1, anticorps F14J22.24, anticorps elongator protein 2, anticorps elongator acetyltransferase complex subunit 2, anticorps elongator protein 2, anticorps elp2, anticorps ELP2, anticorps Elp2

Sujet: One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.

UniProt: Q6IA86

Pathways: Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus