AIM2 anticorps
-
- Antigène Voir toutes AIM2 Anticorps
- AIM2 (Absent in Melanoma 2 (AIM2))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp AIM2 est non-conjugé
-
Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human AIM2
- Isotype
- IgG
- Top Product
- Discover our top product AIM2 Anticorps primaire
-
-
- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.8 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- AIM2 (Absent in Melanoma 2 (AIM2))
- Autre désignation
- AIM2 (AIM2 Produits)
- Synonymes
- anticorps AIM2, anticorps PYHIN4, anticorps Gm1313, anticorps Ifi210, anticorps absent in melanoma 2, anticorps AIM2, anticorps Aim2
- Sujet
- Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NFB transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
- UniProt
- O14862
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
-