AURKAIP1 anticorps

N° du produit ABIN7236305

Détail du produit anti-AURKAIP1 anticorps

Antigène: AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AURKAIP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human AURKAIP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur AURKAIP1

Antigène: AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))

Autre désignation: AURKAIP1 (AURKAIP1 Produits)

Synonymes: anticorps zgc:171708, anticorps AIP, anticorps AKIP, anticorps 0610033H09Rik, anticorps Aip, anticorps Akip, anticorps aurora kinase A interacting protein 1, anticorps AURKAIP1, anticorps aurkaip1, anticorps Aurkaip1

Sujet: AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Poids moléculaire: 22 kDa

UniProt: Q9NWT8