anticorps ALDA, anticorps GSD12, anticorps aldoa, anticorps cb79, anticorps sb:cb79, anticorps wu:fa28b10, anticorps wu:fb10b11, anticorps ALDOA, anticorps Aldo-1, anticorps Aldo1, anticorps RNALDOG5, anticorps hm:zeh0036, anticorps zgc:77696, anticorps aldolase, fructose-bisphosphate A, anticorps aldolase a, fructose-bisphosphate, a, anticorps aldolase, fructose-bisphosphate A S homeolog, anticorps aldolase A, fructose-bisphosphate, anticorps aldolase a, fructose-bisphosphate, b, anticorps ALDOA, anticorps aldoaa, anticorps aldoa, anticorps aldoa.S, anticorps Aldoa, anticorps aldoab
Sujet
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.