DMRT3 anticorps

N° du produit ABIN7236822

Détail du produit anti-DMRT3 anticorps

Antigène: DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMRT3 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human DMRT3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DMRT3

Antigène: DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))

Autre désignation: DMRT3 (DMRT3 Produits)

Synonymes: anticorps DMRTA3, anticorps DMRT3, anticorps dmrt3a2, anticorps zDmrt3a-2, anticorps zDmrt3b, anticorps dmrt3a1, anticorps zDmart3a, anticorps zgc:101766, anticorps doublesex and mab-3 related transcription factor 3, anticorps doublesex and mab-3 related transcription factor 3b, anticorps doublesex and mab-3 related transcription factor 3a, anticorps DMRT3, anticorps Dmrt3, anticorps dmrt3, anticorps dmrt3b, anticorps dmrt3a

Sujet: The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Poids moléculaire: 51 kDa

UniProt: Q9NQL9