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Filamin A anticorps

FLNA Reactivité: Humain, Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7237020
  • Antigène Voir toutes Filamin A (FLNA) Anticorps
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Reactivité
    • 98
    • 25
    • 21
    • 3
    • 1
    • 1
    Humain, Souris
    Hôte
    • 90
    • 7
    • 1
    Lapin
    Clonalité
    • 80
    • 18
    Polyclonal
    Conjugué
    • 46
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Filamin A est non-conjugé
    Application
    • 53
    • 32
    • 28
    • 28
    • 27
    • 26
    • 13
    • 11
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human FLNA
    Isotype
    IgG
    Top Product
    Discover our top product FLNA Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Autre désignation
    FLNA (FLNA Produits)
    Sujet
    The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    281 kDa
    NCBI Accession
    NP_001104026
    UniProt
    P21333
    Pathways
    TCR Signaling, Maintenance of Protein Location
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