CD42b anticorps

N° du produit ABIN7237134

Détail du produit anti-CD42b anticorps

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human GP1BA

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: CD42b (GP1BA Produits)

Synonymes: anticorps BDPLT1, anticorps BDPLT3, anticorps BSS, anticorps CD42B, anticorps CD42b-alpha, anticorps DBPLT3, anticorps GP1B, anticorps GPIbA, anticorps VWDP, anticorps GP1BA, anticorps GPIba, anticorps GPIbalpha, anticorps glycoprotein Ib platelet alpha subunit, anticorps glycoprotein Ib (platelet), alpha polypeptide, anticorps glycoprotein 1b, alpha polypeptide, anticorps GP1BA, anticorps Gp1ba

Sujet: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

Poids moléculaire: 72 kDa

UniProt: P07359