IKbIP anticorps

N° du produit ABIN7237250

Détail du produit anti-IKbIP anticorps

Antigène: IKbIP (Inhibitor of KB Kinase beta Interacting Protein (IKbIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKbIP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human IKBIP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IKbIP

Antigène: IKbIP (Inhibitor of KB Kinase beta Interacting Protein (IKbIP))

Autre désignation: IKBIP (IKbIP Produits)

Synonymes: anticorps IKIP, anticorps 1200009F10Rik, anticorps 1700023M03Rik, anticorps D18354, anticorps Ikip, anticorps RGD1305457, anticorps IKBKB interacting protein, anticorps IKBIP, anticorps Ikbip

Sujet: IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

UniProt: Q70UQ0