anticorps 5330431N24Rik, anticorps AI851877, anticorps ARTD11, anticorps HIN1L, anticorps C12orf6, anticorps parp11, anticorps MGC82612, anticorps PARP11, anticorps RGD1561791, anticorps poly (ADP-ribose) polymerase family, member 11, anticorps poly(ADP-ribose) polymerase family member 11, anticorps poly(ADP-ribose) polymerase family member 11 S homeolog, anticorps poly(ADP-ribose) polymerase family member 11 L homeolog, anticorps Parp11, anticorps PARP11, anticorps parp11.S, anticorps parp11.L, anticorps parp11
Sujet
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.