anticorps DKFZp459F101, anticorps AW060611, anticorps Mdc, anticorps MDC, anticorps mdc, anticorps mdc11a, anticorps xMDC11, anticorps ADAM metallopeptidase domain 11, anticorps a disintegrin and metallopeptidase domain 11, anticorps ADAM metallopeptidase domain 11 L homeolog, anticorps ADAM11, anticorps adam11, anticorps Adam11, anticorps adam11.L
Sujet
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.