Ankyrin G anticorps

N° du produit ABIN7238654

Détail du produit anti-Ankyrin G anticorps

Antigène: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ankyrin G est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human ANK3

Isotype: IgG

Information d'application

Indications d'application: IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Ankyrin G

Antigène: Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

Autre désignation: ANK3 (ANK3 Produits)

Synonymes: anticorps ANK3, anticorps ankyrin-G, anticorps 2900054D09Rik, anticorps AI314020, anticorps Ank-3, anticorps AnkG, anticorps Ankyrin-3, anticorps Ankyrin-G, anticorps ANKYRIN-G, anticorps ankyrin 3, anticorps ankyrin 3, node of Ranvier (ankyrin G), anticorps ankyrin 3, epithelial, anticorps ANK3, anticorps legA6, anticorps PB000272.02.0, anticorps PY00018, anticorps ank3, anticorps Ank3

Sujet: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats, a central region with a highly conserved spectrin binding domain, and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_001191332

UniProt: Q12955

Pathways: Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development